BDBM7684 4-[2-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-hydrazino]benzenesulfonamide::4-{2-[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzene-1-sulfonamide::Oxindole-Based Inhibitor 20

SMILES NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3ccc(Cl)cc23)cc1

InChI Key InChIKey=OSOOMYVRUVOQLW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 7684   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7684(4-[2-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-yliden...)
Affinity DataIC50:  300nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7684(4-[2-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-yliden...)
Affinity DataIC50:  43nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7684(4-[2-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-yliden...)
Affinity DataIC50:  43nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7684(4-[2-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-yliden...)
Affinity DataIC50:  43nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7684(4-[2-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-yliden...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Cyclin-Dependent Kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7684(4-[2-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-yliden...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed