BDBM7770 N-(2-Hydroxyethyl)(4-{[(7-oxo-6,7-dihydro-8H-[1,3]-thiazolo[5,4-e]indol-8-ylidene)methyl]amino}phenyl)-methanesulfonamide::N-(2-hydroxyethyl)[4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8-tetraen-12-ylidene]methyl}amino)phenyl]methanesulfonamide::Oxindole-Based Inhibitor 106

SMILES OCCNS(=O)(=O)Cc1ccc(cc1)N=CC1C(=O)Nc2ccc3ncsc3c12

InChI Key InChIKey=FBKWYVTXXGSTQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7770   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7770(N-(2-Hydroxyethyl)(4-{[(7-oxo-6,7-dihydro-8H-[1,3]...)
Affinity DataIC50:  13nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7770(N-(2-Hydroxyethyl)(4-{[(7-oxo-6,7-dihydro-8H-[1,3]...)
Affinity DataIC50:  200nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed