BDBM7771 (12Z)-12-({[4-(methanesulfonylmethyl)phenyl]amino}methylidene)-3-thia-5,10-diazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8-tetraen-11-one::8-({4-[(Methylsulfonyl)methyl]anilino}methylene)-6,8-dihydro-7H-[1,3]thiazolo[5,4-e]indol-7-one::Oxindole-Based Inhibitor 107

SMILES CS(=O)(=O)Cc1ccc(cc1)N=CC1C(=O)Nc2ccc3ncsc3c12

InChI Key InChIKey=QPATWQLFAUBHBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7771   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7771((12Z)-12-({[4-(methanesulfonylmethyl)phenyl]amino}...)
Affinity DataIC50:  50nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7771((12Z)-12-({[4-(methanesulfonylmethyl)phenyl]amino}...)
Affinity DataIC50:  1.20E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed