BDBM7772 5-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8-tetraen-12-ylidene]methyl}amino)-1,3-dihydro-2-benzothiophene-2,2-dione::8-{[(2,2-Dioxido-1,3-dihydro-2-benzothien-5-yl)amino]-methylene}-6,8-dihydro-7H-[1,3]thiazolo[5,4-e]indol-7-one::CS245::Oxindole-Based Inhibitor 108

SMILES O=C1Nc2ccc3ncsc3c2C1C=Nc1ccc2CS(=O)(=O)Cc2c1

InChI Key InChIKey=CEZKUHAOXFVYTL-UHFFFAOYSA-N

Data  2 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 7772   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7772(5-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50:  31nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7772(5-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50:  14nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7772(5-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataKd:  36nMpH: 7.5 T: 2°CAssay Description:OctetRedMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Csar

LigandPNGBDBM7772(5-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataKd:  163nMpH: 7.5 T: 2°CAssay Description:ThermofluorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Csar

LigandPNGBDBM7772(5-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataKd:  229nMpH: 7.5 T: 2°CAssay Description:OctetRedMore data for this Ligand-Target Pair
In DepthDetails PubMed