BDBM79214 1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthren-9-yl]-3-(dibutylamino)propan-1-ol;hydrochloride::3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)-9-phenanthrenyl]-1-propanol;hydrochloride::3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)-9-phenanthryl]propan-1-ol;hydrochloride::3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol;hydrochloride::HALOFANTRINE::Halofantrine hydrochloride::MLS002154111::SMR001233418::cid_37392

SMILES CCCCN(CCCC)CCC(O)c1cc2c(Cl)cc(Cl)cc2c2cc(ccc12)C(F)(F)F

InChI Key InChIKey=FOHHNHSLJDZUGQ-UHFFFAOYSA-N

Data  1 KI  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 79214   

LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetUbiquitin-conjugating enzyme E2 N(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50: >2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Potassium channel HERG expressed in mammalian cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against IKr potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human voltage-gated potassium channel subunit Kv11.1 (ERG K+ channel) in open stateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  160nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human ERG expressed in CHO cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  196nMAssay Description:K+ channel blocking activity in Chinese hamster ovary cells expressing HERG Kv11.1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  156nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  195nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human ERG in MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank