BDBM8 (1R)-cyclohexane-1,2-diol::cis-1,2-cyclohexanediol::trans-1,2-cyclohexanediol
SMILES OC1CCCC[C@H]1O
InChI Key InChIKey=PFURGBBHAOXLIO-LWOQYNTDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 4 hits for monomerid = 8
HostBDBM4((1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23...)
National Institute Of Standards And Technology
National Institute Of Standards And Technology
ITC DataΔG°: -1.65kcal/mole −TΔS°: 0.997kcal/mole ΔH°: -2.63kcal/mole logk: 16
pH: 6.9 T: 25.00°C
pH: 6.9 T: 25.00°C
In DepthDetails
HostBDBM4((1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23...)
National Institute Of Standards And Technology
National Institute Of Standards And Technology
ITC DataΔG°: -1.67kcal/mole −TΔS°: 0.926kcal/mole ΔH°: -2.63kcal/mole logk: 17
pH: 6.9 T: 25.00°C
pH: 6.9 T: 25.00°C
In DepthDetails
ITC DataΔG°: -3.32kcal/mole −TΔS°: -0.997kcal/mole ΔH°: -2.34kcal/mole logk: 267
pH: 6.9 T: 25.00°C
pH: 6.9 T: 25.00°C
In DepthDetails