BDBM82269 (+)-alpha-Propoxyphene::CAS_469-62-5::PROPOXYPHENE::Propoxyphene-d

SMILES CCC(=O)O[C@@](Cc1ccccc1)([C@H](C)CN(C)C)c1ccccc1

InChI Key InChIKey=XLMALTXPSGQGBX-GCJKJVERSA-N

Data  5 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 82269   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM82269((+)-alpha-Propoxyphene | CAS_469-62-5 | PROPOXYPHE...)
Affinity DataKi:  34.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM82269((+)-alpha-Propoxyphene | CAS_469-62-5 | PROPOXYPHE...)
Affinity DataKi:  380nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM82269((+)-alpha-Propoxyphene | CAS_469-62-5 | PROPOXYPHE...)
Affinity DataKi:  1.22E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM82269((+)-alpha-Propoxyphene | CAS_469-62-5 | PROPOXYPHE...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNorepinephrine transporter(RAT)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM82269((+)-alpha-Propoxyphene | CAS_469-62-5 | PROPOXYPHE...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMas-related G-protein coupled receptor member X2(Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM82269((+)-alpha-Propoxyphene | CAS_469-62-5 | PROPOXYPHE...)
Affinity DataEC50:  1.50E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMas-related G-protein coupled receptor member X2(Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM82269((+)-alpha-Propoxyphene | CAS_469-62-5 | PROPOXYPHE...)
Affinity DataEC50:  3.20E+4nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TCG Lifesciences Ltd.

Curated by ChEMBL
LigandPNGBDBM82269((+)-alpha-Propoxyphene | CAS_469-62-5 | PROPOXYPHE...)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed