BDBM841 Benzocycloalkyl Amines deriv. 11::tert-butyl N-[(2S,3S,5R)-5-benzyl-5-{[(1R,2R)-2-carbamoyl-2,3-dihydro-1H-inden-1-yl]carbamoyl}-3-hydroxy-1-phenylpentan-2-yl]carbamate
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@@H](Cc2ccccc12)C(N)=O
InChI Key InChIKey=ROOKYLNNFCRHNK-WJBPYKOESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 841
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories
Merck Sharp And Dohme Research Laboratories
Affinity DataIC50: 1.80nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair