BDBM86525 AMI-193::CAS_77445::CHEMBL79834::NSC_77445

SMILES Fc1ccc(OCCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)cc1

InChI Key InChIKey=FJUKDAZEABGEIH-UHFFFAOYSA-N

Data  8 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 86525   

TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataKi:  2nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortical regions using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataKi:  3nMAssay Description:Tested for binding affinity against dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Vernalis Research

Curated by PDSP Ki Database
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataKi:  22.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataKi:  50nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 1A receptor from rat frontal cortical regions using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Vernalis Research

Curated by PDSP Ki Database
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataKi:  977nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Vernalis Research

Curated by PDSP Ki Database
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataKi:  1.55E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Mus musculus (Mouse))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataKi:  2.53E+3nMAssay Description:Tested for binding affinity against dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataKi:  4.30E+3nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 1C receptor from rat frontal cortical regions using [3H]-mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Vernalis Research

Curated by PDSP Ki Database
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataIC50:  0.316nMAssay Description:Compound was evaluated for its inverse agonist activity against 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes Of Health Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM86525(AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445)
Affinity DataEC50:  3.16E+4nMAssay Description:Competitive binding affinity to human PXR LBD (111 to 434) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed