TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.960nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:The compound was tested for the inhibitory activity against prolyl endo peptidase(PEP) enzymeMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The compound was tested for the inhibitory activity against prolyl endo peptidase(PEP) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 184nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 355nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 859nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Tubulin polymerization inhibitory activity using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Tubulin polymerization inhibitory activity using bovine brain tubulinMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Tubulin polymerization inhibitory activity using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Tubulin polymerization inhibitory activity using bovine brain tubulinMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Tubulin polymerization inhibitory activity using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Tubulin polymerization inhibitory activity using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Tubulin polymerization inhibitory activity using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Tubulin polymerization inhibitory activity using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against tubulin polymerizationMore data for this Ligand-Target Pair