BindingDB PrimarySearch_ki

Found 915 with Last Name = 'blumberg' and Initial = 'lc'

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179904(US10231963, Table C.8 | US10287250, Compound D.8 |...)

Ki: 0.0500nM ΔG°: -58.8kJ/mole IC50: 58nMpH: 7.5 T: 2°CAssay Description:The Ki (binding affinity) for u opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal o...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179904(US10231963, Table C.8 | US10287250, Compound D.8 |...)

Ki: 0.0500nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179904(US10231963, Table C.8 | US10287250, Compound D.8 |...)

Ki: 0.0500nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179904(US10231963, Table C.8 | US10287250, Compound D.8 |...)

Ki: 0.0500nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179904(US10231963, Table C.8 | US10287250, Compound D.8 |...)

Ki: 0.0500nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179904(US10231963, Table C.8 | US10287250, Compound D.8 |...)

Ki: 0.0500nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179904(US10231963, Table C.8 | US10287250, Compound D.8 |...)

Ki: 0.0500nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)

Ki: 0.0610nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50249017(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)

Ki: 0.0610nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)

Ki: 0.0610nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)

Ki: 0.0610nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50249017(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)

Ki: 0.0610nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)

Ki: 0.0610nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50249017(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)

Ki: 0.0610nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM456904(US10736890, Compound TABLE B.14)

Ki: 0.0610nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM309330(US10231963, Table B.2 | US11534436, Compound Table...)

Ki: 0.0790nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase PC cid PC sid

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM309330(US10231963, Table B.2 | US11534436, Compound Table...)

Ki: 0.0790nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase PC cid PC sid

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM309330(US10231963, Table B.2 | US11534436, Compound Table...)

Ki: 0.0790nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase PC cid PC sid

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM456892(US10736890, Compound TABLE B.2)

Ki: 0.0790nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)

Ki: 0.0800nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)

Ki: 0.0800nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)

Ki: 0.0800nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)

Ki: 0.0800nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179897(US10287250, Compound 1 | US10736890, Compound TABL...)

Ki: 0.0830nM ΔG°: -57.5kJ/mole IC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The Ki (binding affinity) for u opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal o...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM369489(US10231963, Table C.1)

Ki: 0.0830nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM457874(US10752592, Compound B)

Ki: 0.0830nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179897(US10287250, Compound 1 | US10736890, Compound TABL...)

Ki: 0.0830nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179897(US10287250, Compound 1 | US10736890, Compound TABL...)

Ki: 0.0830nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179897(US10287250, Compound 1 | US10736890, Compound TABL...)

Ki: 0.0830nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179897(US10287250, Compound 1 | US10736890, Compound TABL...)

Ki: 0.0830nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179897(US10287250, Compound 1 | US10736890, Compound TABL...)

Ki: 0.0830nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179877(US10231963, Table B.23 | US10736890, Compound TABL...)

Ki: 0.0970nM ΔG°: -57.2kJ/mole IC50: 1.10nMpH: 7.5 T: 2°CAssay Description:The Ki (binding affinity) for u opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal o...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179875(US10231963, Table B.21 | US10752592, Compound TABL...)

Ki: 0.0970nM ΔG°: -57.2kJ/mole IC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The Ki (binding affinity) for u opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal o...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179877(US10231963, Table B.23 | US10736890, Compound TABL...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179877(US10231963, Table B.23 | US10736890, Compound TABL...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179875(US10231963, Table B.21 | US10752592, Compound TABL...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM50165048(17-cyclobutylmethyl-3,10-dihydroxy-13-oxo-(1R,9R,1...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179874(US10231963, Table B.18 | US10287250, Compound B.3 ...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179877(US10231963, Table B.23 | US10736890, Compound TABL...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179875(US10231963, Table B.21 | US10752592, Compound TABL...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179875(US10231963, Table B.21 | US10752592, Compound TABL...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179877(US10231963, Table B.23 | US10736890, Compound TABL...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179874(US10231963, Table B.18 | US10287250, Compound B.3 ...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179877(US10231963, Table B.23 | US10736890, Compound TABL...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179875(US10231963, Table B.21 | US10752592, Compound TABL...)

Ki: 0.0970nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179902(US10231963, Table C.6 | US10287250, Compound D.6 |...)

Ki: 0.0980nM ΔG°: -57.1kJ/mole IC50: 7.80nMpH: 7.5 T: 2°CAssay Description:The Ki (binding affinity) for u opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal o...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179902(US10231963, Table C.6 | US10287250, Compound D.6 |...)

Ki: 0.0980nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179902(US10231963, Table C.6 | US10287250, Compound D.6 |...)

Ki: 0.0980nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179902(US10231963, Table C.6 | US10287250, Compound D.6 |...)

Ki: 0.0980nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Mu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent

PNG

BDBM179902(US10231963, Table C.6 | US10287250, Compound D.6 |...)

Ki: 0.0980nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details US Patent

Displayed 1 to 50 (of 915 total ) | Next | Last >>

Filter my 915 hits

Targets 5▿
- Mu-type opioid receptor 725
- Thrombopoietin receptor 155
- Delta-type opioid receptor 13
- Kappa-type opioid receptor 12
- C-C chemokine receptor type 1 10
Publications 12▿
- US Patent US9656961 (2017) 158
- Bioorg Med Chem Lett 17: 5447-54 (2007) 116
- US Patent US10752592 (2020) 113
- US Patent US10287250 (2019) 110
- US Patent US10231963 (2019) 109
- US Patent US10736890 (2020) 75
- US Patent US11534436 (2022) 75
- US Patent US9133125 (2015) 72
- US Patent US8962646 (2015) 38
- Bioorg Med Chem Lett 19: 1428-30 (2009) 20
- Bioorg Med Chem Lett 20: 4069-72 (2010) 19
- Bioorg Med Chem Lett 17: 3109-12 (2007) 10
Institutions 3▿
- Alkermes Pharma Ireland 712
- Pfizer 165
- Alkermes 38
Affinity: 0.050 to 1.0E+4 nM▿
- Ki 328
- IC50 285
- EC50 340
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 7