Affinity DataKi: 0.0560nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0620nMAssay Description:Dissociation constant obtained by inhibition of Wild-type proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0620nMAssay Description:Dissociation constant obtained by inhibition of Wild-type proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0840nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Dissociation constant obtained by inhibition of Wild-type proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Dissociation constant obtained by inhibition of Wild-type proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.280nM Koff: 2.51E+3s-1Assay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.610nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:In vitro inhibitory activity against human thrombin(IIa)More data for this Ligand-Target Pair
Affinity DataKi: 0.850nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 2nM Koff: 2.10E+3s-1Assay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:In vitro inhibitory activity against human thrombin(IIa)More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3nM Koff: 1.80E+3s-1Assay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:In vitro inhibitory activity against human thrombin(IIa)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:In vitro inhibitory activity against human thrombin(IIa)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 3.40nM Koff: 1.55E+3s-1Assay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:In vitro inhibitory activity against human thrombin(IIa)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (K-60)More data for this Ligand-Target Pair