Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMpH: 7.4 T: 2°CAssay Description:A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 無, and all the samples were diluted with an assay buffe...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HPGDSMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Agonist activity at FPR2 in human HL-60 cells assessed as reduction in chemoattractant induced chemotaxis by luminescence cell viability assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human HPGDS using [14C]-PGH2 as substrate preincubated for 1 min in presence of MgCl2 followed by substrate addition and me...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 266nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARalpha LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARalpha LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARalpha LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 396nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 808nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 351nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 458nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 129nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 615nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 71nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 1.13E+3nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 746nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 1.17E+3nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 94nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: 90nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair