Found 889 with Last Name = 'mann' and Initial = 'jj' 
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nM ΔG°: -52.1kJ/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:In vitro inhibition constant for Aurora-AMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.660nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.835nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Agonist activity assessed by stimulation of [35S]GTP-gamma-S binding to human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]rauwolscine from adrenergic alpha2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -44.6kJ/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]rauwolscine from adrenergic alpha2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:In vitro inhibition constant for Aurora-CMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nM ΔG°: -43.8kJ/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -43.6kJ/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair
Affinity DataKi: 8nM ΔG°: -45.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
