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Found 141 with Last Name = 'mayfield' and Initial = 'ca'
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  70nMAssay Description:The compound was tested for the inhibition of Aldose reductase in rat lens assay.More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  73nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016618(CHEMBL8370 | [(3-Nitro-benzoyl)-(4-nitro-phenyl)-a...)
Affinity DataIC50:  130nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.02 -0.64More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  180nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  230nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.07 - 1.2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50010002(CHEMBL302057 | [(4-Benzoylamino-benzoyl)-phenyl-am...)
Affinity DataIC50:  240nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016553(CHEMBL36108 | [(4-Benzoylamino-benzenesulfonyl)-ph...)
Affinity DataIC50:  380nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016557((Naphthalene-2-sulfonylamino)-acetic acid | CHEMBL...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016550((4-Benzoylamino-benzenesulfonylamino)-acetic acid ...)
Affinity DataIC50:  410nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009985(CHEMBL69716 | [(4-Nitro-benzoyl)-phenyl-amino]-ace...)
Affinity DataIC50:  560nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016609((2-Oxo-2H-benzo[cd]indol-1-yl)-acetic acid | CHEMB...)
Affinity DataIC50:  670nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.15 - 3.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022333(CHEMBL41232 | [4-(3-Phenyl-acryloylamino)-benzenes...)
Affinity DataIC50:  690nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016598(CHEMBL8786 | [Benzoyl-(3-nitro-phenyl)-amino]-acet...)
Affinity DataIC50:  860nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.3 - 2.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016550((4-Benzoylamino-benzenesulfonylamino)-acetic acid ...)
Affinity DataIC50:  880nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016604(CHEMBL267531 | [Benzoyl-(4-methoxy-phenyl)-amino]-...)
Affinity DataIC50:  960nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.1 - 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016572(CHEMBL286389 | [(3-Nitro-benzenesulfonyl)-phenyl-a...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016549(CHEMBL37072 | [(4-Methoxy-benzenesulfonyl)-phenyl-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022337((4-Phenylacetylamino-benzenesulfonylamino)-acetic ...)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50367835(CHEMBL1907953)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022338(CHEMBL417523 | [4-(2-Phenoxy-acetylamino)-benzenes...)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022334(CHEMBL40666 | [4-(3-Phenyl-ureido)-benzenesulfonyl...)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009990(CHEMBL305251 | [(4-Benzoylamino-benzoyl)-methyl-am...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016596((Benzoyl-p-tolyl-amino)-acetic acid | CHEMBL275007)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.5 - 16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009983(CHEMBL308898 | [(4-Methoxy-benzoyl)-phenyl-amino]-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022342(CHEMBL40681 | [4-(2-Benzyloxy-acetylamino)-benzene...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016591(CHEMBL34976 | [(2-Nitro-benzenesulfonyl)-phenyl-am...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009992(CHEMBL69549 | [(4-Methyl-benzoyl)-phenyl-amino]-ac...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022345((4-Acetylamino-benzenesulfonylamino)-acetic acid |...)
Affinity DataIC50:  4.22E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016551(CHEMBL37003 | [(4-Nitro-benzenesulfonyl)-phenyl-am...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016576(CHEMBL35870 | [(Naphthalene-2-sulfonyl)-phenyl-ami...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016600(CHEMBL274433 | [Benzoyl-(4-chloro-phenyl)-amino]-a...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 1.5 - 16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016582(2-(Naphthalene-2-sulfonylamino)-benzoic acid | CHE...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009980(CHEMBL266688 | [(Naphthalene-1-carbonyl)-phenyl-am...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 1.0 - 34More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016594(CHEMBL8607 | [Acetyl-(4-nitro-phenyl)-amino]-aceti...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.6 - 47More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022336((4-Benzyloxycarbonylamino-benzenesulfonylamino)-ac...)
Affinity DataIC50:  6.03E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009997((Benzoyl-phenyl-amino)-acetic acid | CHEMBL273228)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009978(CHEMBL66711 | [(4-Methoxy-benzoyl)-methyl-amino]-a...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022339((4-Benzylamino-benzenesulfonylamino)-acetic acid |...)
Affinity DataIC50:  7.04E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50367829(CHEMBL1907951)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022343((3-Benzoylamino-benzenesulfonylamino)-acetic acid ...)
Affinity DataIC50:  7.12E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016593(CHEMBL37193 | [Benzenesulfonyl-(2-chloro-phenyl)-a...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016585(2-(4-Amino-benzenesulfonylamino)-benzoic acid | CH...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009984(CHEMBL66216 | [(4-Fluoro-benzoyl)-phenyl-amino]-ac...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016571(2-(Naphthalene-1-sulfonylamino)-benzoic acid | CHE...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50022340(CHEMBL39090 | [4-(3-Phenyl-thioureido)-benzenesulf...)
Affinity DataIC50:  8.42E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009980(CHEMBL266688 | [(Naphthalene-1-carbonyl)-phenyl-am...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50367837(CHEMBL1907773)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016556(CHEMBL284603 | [Benzenesulfonyl-(3-nitro-phenyl)-a...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibitory concentration against aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009988(CHEMBL308007 | [(4-Fluoro-benzoyl)-methyl-amino]-a...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibitory activity against aldose reductase in rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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