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Found 267 with Last Name = 'ouchi' and Initial = 'h'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111903((S)-1-[(S)-2-{2-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  0.000540nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111905((S)-4-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataKi:  0.00105nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataKi:  0.00260nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096716(CHEMBL100480 | Enkephalin derivative)
Affinity DataKi:  0.00680nMAssay Description:Binding affinity was determined towards Opioid receptor mu 1 in rat brain synaptosomes using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096719((S)-2-[(R)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-2,6-d...)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity was determined towards Opioid receptor mu 1 in rat brain synaptosomes using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096716(CHEMBL100480 | Enkephalin derivative)
Affinity DataKi:  0.0310nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 in rat brain synaptosomes using [3H]-deltorphin II as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059841((S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  0.0920nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096719((S)-2-[(R)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-2,6-d...)
Affinity DataKi:  0.158nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 in rat brain synaptosomes using [3H]-deltorphin II as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189854(6-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189841(6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189852(8-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]...)
Affinity DataKi:  0.530nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189843(2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-meth...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189844(2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-5-(pyr...)
Affinity DataKi:  0.940nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189851(8-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189839(6-bromo-2-[4-(3,4-dichlorophenyl)piperazin-1-ylmet...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094503(2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-in...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189856(6-chloro-2-[4-(3,4-dichlorophenyl)piperazin-1-ylme...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096720((S)-2-[(R)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity was determined towards Opioid receptor mu 1 in rat brain synaptosomes using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189853(2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-meth...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 in rat brain synaptosomes using [3H]-deltorphin II as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189848(2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]imid...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189840(6-chloro-2-[4-(2-methoxyphenyl)piperazin-1-ylmethy...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189847(2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-meth...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Bos taurus)
Toyama Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50065258((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Affinity DataKi:  1.70nMAssay Description:Ki value against bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189849(6-chloro-2-[4-(4-chlorophenyl)piperazin-1-ylmethyl...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189857(2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-meth...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity was determined towards Opioid receptor mu 1 in rat brain synaptosomes using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189845(2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50073805(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189846(6-chloro-2-[4-(4-fluorophenyl)piperazin-1-ylmethyl...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111906((S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity of the compound against Opioid receptor mu 1 using [3H]-DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Bos taurus)
Toyama Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50065257((2R,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidi...)
Affinity DataKi:  5.30nMAssay Description:Ki value against bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096718((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-2,6-d...)
Affinity DataKi:  5.60nMAssay Description:Binding affinity was determined towards Opioid receptor mu 1 in rat brain synaptosomes using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189842(2-[4-(4-chlorophenyl)piperazin-1-yl)methyl]imidazo...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096720((S)-2-[(R)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  18nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 in rat brain synaptosomes using [3H]-deltorphin II as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189840(6-chloro-2-[4-(2-methoxyphenyl)piperazin-1-ylmethy...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in porcine cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189843(2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-meth...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096718((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-2,6-d...)
Affinity DataKi:  41nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 in rat brain synaptosomes using [3H]-deltorphin II as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189837(2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111903((S)-1-[(S)-2-{2-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  46nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 using [3H]-DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189843(2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-meth...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189841(6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189841(6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189840(6-chloro-2-[4-(2-methoxyphenyl)piperazin-1-ylmethy...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Bos taurus)
Toyama Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50163439((2S,3R,4S,5R)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataKi:  80nMAssay Description:Ki value against bovine alpha-L-fucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189852(8-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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