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Found 124 with Last Name = 'plouffe' and Initial = 'c'
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137962((1R,2S)-1-((3R,5S)-1-((S)-2-((S)-2-acetamido-2-cyc...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061511((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  70nMAssay Description:Activity against serine protease porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061512((S)-N*1*-(2-Benzooxazol-2-yl-1-methyl-2-oxo-ethyl)...)
Affinity DataIC50:  80nMAssay Description:Activity against serine protease porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061532((S)-N*1*-{2-[(Benzo[1,3]dioxol-5-ylmethyl)-carbamo...)
Affinity DataIC50:  100nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061537((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  110nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137963((1R,2S)-1-((3R,5S)-1-((S)-2-((S)-2-acetamido-2-cyc...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061518((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  110nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137959(1-{[(R)-(S)-1-[(S)-2-((S)-2-Acetylamino-2-cyclohex...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061515((S)-N*1*-[2-(2-Benzyloxy-ethylcarbamoyl)-1-methyl-...)
Affinity DataIC50:  140nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061509((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  200nMAssay Description:Activity against serine protease porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061503((S)-N*1*-(2-Benzylcarbamoyl-1-methyl-2-oxo-ethyl)-...)
Affinity DataIC50:  200nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061528((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  200nMAssay Description:Activity against serine protease porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061506((S)-N*1*-{2-[(1H-Benzoimidazol-2-ylmethyl)-carbamo...)
Affinity DataIC50:  210nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061544((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  280nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061497((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  300nMAssay Description:Activity against serine protease porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137965(1-((2S,4R)-1-((S)-2-((S)-2-acetamido-2-cyclohexyla...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50093011(1-((2S,4R)-1-((S)-2-((S)-2-acetamido-2-cyclohexyla...)
Affinity DataIC50:  390nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50093011(1-((2S,4R)-1-((S)-2-((S)-2-acetamido-2-cyclohexyla...)
Affinity DataIC50:  390nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061530((S)-N*1*-((S)-3-Benzylcarbamoyl-3,3-difluoro-1-met...)
Affinity DataIC50:  460nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061512((S)-N*1*-(2-Benzooxazol-2-yl-1-methyl-2-oxo-ethyl)...)
Affinity DataIC50:  600nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061509((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  600nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061528((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  600nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061516((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  660nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061511((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  900nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061551((S)-2-{(S)-2-[3-(4-Hydroxy-phenyl)-propionylamino]...)
Affinity DataIC50:  1.00E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061498((S)-2-((S)-2-(3,3-dimethylbutanamido)-3,3-dimethyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061505((S)-2-[(S)-2-((S)-2-Acetylamino-3-methyl-butyrylam...)
Affinity DataIC50:  1.10E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061510((S)-N*1*-(2-Benzothiazol-2-yl-1-methyl-2-oxo-ethyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061553((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  1.10E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061540((S)-2-[(S)-3,3-Dimethyl-2-(3-methyl-butyrylamino)-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061534(4-{(S)-1-[(S)-2-Dimethylcarbamoyl-1-(3,3,3-trifluo...)
Affinity DataIC50:  1.60E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061526((S)-2-{(S)-2-[(S)-2-(2-Acetylamino-acetylamino)-3-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061538((S)-2-[(S)-2-((S)-2-Acetylamino-3-methyl-butyrylam...)
Affinity DataIC50:  2.00E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061523((S)-2-[(S)-2-(3-tert-Butyl-ureido)-3,3-dimethyl-bu...)
Affinity DataIC50:  2.40E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061521((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-2-hydroxy-a...)
Affinity DataIC50:  2.60E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061497((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  2.80E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061546((S)-2-((S)-2-Acetylamino-3,3-dimethyl-butyrylamino...)
Affinity DataIC50:  2.80E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061522((S)-2-[(S)-2-((S)-2-Acetylamino-3-methyl-butyrylam...)
Affinity DataIC50:  3.00E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137960((R)-1-{[(S)-1-((S)-2-Acetylamino-3-methyl-butyryl)...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061520((S)-2-[(S)-2-(3,3-Dimethyl-butylamino)-3,3-dimethy...)
Affinity DataIC50:  3.20E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061536((S)-2-[(S)-2-(2-Dimethylamino-acetylamino)-3,3-dim...)
Affinity DataIC50:  3.40E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061531((S)-2-[(S)-2-((S)-2-Acetylamino-3-methyl-butyrylam...)
Affinity DataIC50:  3.60E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061539((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  3.70E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137964(1-((2S,4R)-1-((S)-2-((S)-2-acetamido-2-cyclohexyla...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50093011(1-((2S,4R)-1-((S)-2-((S)-2-acetamido-2-cyclohexyla...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity of the compound against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061514((S)-2-[(S)-2-((S)-2-Acetylamino-3-methyl-butyrylam...)
Affinity DataIC50:  4.40E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061542((S)-2-Acetylamino-3-methyl-N-{(S)-2-methyl-1-[(S)-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061503((S)-N*1*-(2-Benzylcarbamoyl-1-methyl-2-oxo-ethyl)-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Activity against serine protease porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50366665(CHEMBL1790526)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory concentration required against NS3 Protease of Hepatitis C VirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061547(CHEMBL133346 | {(S)-1-[(S)-2-Dimethylcarbamoyl-1-(...)
Affinity DataIC50:  6.00E+3nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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