TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Antagonist activity at kappa opioid receptor in guinea pig caudate assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Tested in vitro for binding affinity against Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Tested in vitro for binding affinity against mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] bindin...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]diprenorphine from human KORMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Antagonist activity at mu opioid receptor in guinea pig caudate assessed as inhibition of DAMGO-stimulated [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity to NPYY2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]diprenorphine from mu opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataKi: 9.10nMAssay Description:Binding affinity to NPYY2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataKi: 9.90nMAssay Description:Binding affinity to NPYY2 receptor (unknown origin) preincubated for 20 minsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Antagonist activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Binding affinity to NPYY2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]diprenorphine from mu opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranesMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Binding affinity for human neuromedin B(hNMB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 115nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 121nMAssay Description:Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 127nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair