Found 180 with Last Name = 'salyer' and Initial = 'ac' 
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR7 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of imid...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR5 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of flag...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR4 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of LPS-...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR3 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of poly...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR2 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as inhibition of Pam2CS-induced N...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR9 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of ODN2...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2alpha using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1G(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1gamma using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1delta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1B(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1alpha using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK4 using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric hotspo...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2gamma using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2delta using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
Affinity DataIC50: 6.72E+3nMAssay Description:Inhibition of TLR8 in human CD14-positive monocytes cells in presence of TLR7 stimulusMore data for this Ligand-Target Pair
Affinity DataIC50: 7.46E+3nMAssay Description:Inhibition of TLR8 in human CD14-positive monocytes cells in presence of TLR4 stimulusMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced TNFalpha production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced IL-6 production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced IL-8 production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced IFNgamma production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced MCP1 production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced IL12 p40 production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 55nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 621nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 85nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+3nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 519nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 727nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.86E+3nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.18E+3nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 56nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 91nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 699nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 250nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.29E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...More data for this Ligand-Target Pair
Affinity DataEC50: 1.22E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...More data for this Ligand-Target Pair
Affinity DataEC50: 3.40E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...More data for this Ligand-Target Pair
