Compile Data Set for Download or QSAR
maximum 50k data
Found 1002 with Last Name = 'sperandio' and Initial = 'd'
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187167(CHEMBL211357 | N-[(S)-5-amino-1-(5-{4-[2-(3-chloro...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187177(CHEMBL212774 | N-[(2S)-6-amino-1-{5-[(4-{[2-(3-chl...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187166(CHEMBL380293 | N-[(S)-5-amino-1-(5-{4-[2-(3-chloro...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187160(CHEMBL213928 | N-[(2S)-6-amino-1-{5-[(4-{[2-(3-chl...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187163((S)-benzyl 1-(5-(4-((3-chlorophenethyl)carbamoyl)b...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187168(CHEMBL377656 | N-[(2S)-6-amino-1-{5-[(4-{[2-(3-chl...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187176((S)-ethyl 1-(5-(4-((3-chlorophenethyl)carbamoyl)be...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM404301(US10017501, Compound 1020-289)
Affinity DataKi:  2nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM404301(US10017501, Compound 1020-289)
Affinity DataKi:  2nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187162((S)-N-(3-chlorophenethyl)-4-((3-(6-amino-2-pivalam...)
Affinity DataKi:  2nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187182((S)-N-(1-(5-(4-((3-chlorophenethyl)carbamoyl)benzy...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411015(CHEMBL539086)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187164((S)-benzyl 1-(5-(4-((2-(thiophen-2-yl)ethyl)carbam...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411006(CHEMBL539088)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM249309(US10017501, Compound 1020-114 | US9458145, 1020-11...)
Affinity DataKi:  2.70nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14312(CHEMBL214368 | CRA23 | ethyl N-[(2S)-6-amino-1-(5-...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187169((S)-benzyl 1-(5-(4-((2-(4-fluorophenoxy)ethyl)carb...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411011(CHEMBL537868)
Affinity DataKi:  2.90nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM14312(CHEMBL214368 | CRA23 | ethyl N-[(2S)-6-amino-1-(5-...)
Affinity DataKi:  3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187179((S)-benzyl 1-(5-(4-((3-phenylpropyl)carbamoyl)benz...)
Affinity DataKi:  3nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187154((S)-benzyl 1-(5-(4-(phenethylcarbamoyl)benzyl)-1,2...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411017(CHEMBL539603)
Affinity DataKi:  3.25nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187157((S)-benzyl 1-(5-(4-((3,5-difluorophenethyl)carbamo...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187165((S)-benzyl 1-(5-(4-(cinnamylcarbamoyl)benzyl)-1,2,...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM249314(US10017501, Compound 1020-298 | US9458145, 1020-29...)
Affinity DataKi:  3.60nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187158((S)-benzyl 1-(5-(4-((2,3-dihydro-1H-inden-2-yl)car...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411009(CHEMBL538574)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411002(CHEMBL556994)
Affinity DataKi:  3.75nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)
Affinity DataKi:  3.80nMAssay Description:Inhibition of Cy5-linked JQ1 probe binding to recombinant human N-terminal TEV-cleavable hexa-histidine tagged BRD4 bromodomain2 after 60 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM249309(US10017501, Compound 1020-114 | US9458145, 1020-11...)
Affinity DataKi:  3.80nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM249305(US10017501, Compound 1020-103 | US9458145, 1020-10...)
Affinity DataKi:  4nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM14311(CRA22 | N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-i...)
Affinity DataKi:  4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411013(CHEMBL534493)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM249312(US10017501, Compound 1020-257 | US9458145, 1020-25...)
Affinity DataKi:  4.70nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50410996(CHEMBL537647)
Affinity DataKi:  4.70nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411005(CHEMBL537646)
Affinity DataKi:  5nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411019(CHEMBL558199)
Affinity DataKi:  5nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50187800((S)-ethyl 1-(5-(4-phenethoxybenzyl)-1,2,4-oxadiazo...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity to human tryptase beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM249314(US10017501, Compound 1020-298 | US9458145, 1020-29...)
Affinity DataKi:  5.40nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50187800((S)-ethyl 1-(5-(4-phenethoxybenzyl)-1,2,4-oxadiazo...)
Affinity DataKi:  5.40nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase(Rattus norvegicus)
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50187800((S)-ethyl 1-(5-(4-phenethoxybenzyl)-1,2,4-oxadiazo...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to rat tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM249312(US10017501, Compound 1020-257 | US9458145, 1020-25...)
Affinity DataKi:  5.60nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411001(CHEMBL558763)
Affinity DataKi:  5.70nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187172((S)-benzyl 6-amino-1-oxo-1-(5-((4-(4-phenylbutyl)p...)
Affinity DataKi:  5.80nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411008(CHEMBL535836)
Affinity DataKi:  5.80nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM249311(US10017501, Compound 1020-239 | US9458145, 1020-23...)
Affinity DataKi:  5.90nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM14316((2R)-N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-ylca...)
Affinity DataKi:  6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM249311(US10017501, Compound 1020-239 | US9458145, 1020-23...)
Affinity DataKi:  6nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411016(CHEMBL559161)
Affinity DataKi:  6.20nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50411007(CHEMBL534492)
Affinity DataKi:  6.5nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1002 total ) | Next | Last >>
Jump to: