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Found 142 with Last Name = 'van steen' and Initial = 'bj'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020178(CHEMBL294633 | CHEMBL555633 | N-[2-(4-Benzofuran-7...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039829(CHEMBL92242 | Cyclohexanecarboxylic acid [2-(4-ben...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50403670(CHEMBL311015)
Affinity DataKi:  0.229nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039822(1-(2-Cyclohexyl-ethyl)-4-(2,3-dihydro-benzo[1,4]di...)
Affinity DataKi:  0.25nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039822(1-(2-Cyclohexyl-ethyl)-4-(2,3-dihydro-benzo[1,4]di...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50403668(CHEMBL312339)
Affinity DataKi:  0.288nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039824(CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...)
Affinity DataKi:  0.295nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039824(CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039818(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039818(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-...)
Affinity DataKi:  0.324nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039798(1-Benzofuran-7-yl-4-phenethyl-piperazine; hydrochl...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039821(CHEMBL93421 | Cyclohexanecarboxylic acid {2-[4-(2,...)
Affinity DataKi:  0.440nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039810(1-Benzofuran-7-yl-4-(2-phenoxy-ethyl)-piperazine; ...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039800(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-phenethyl-...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039819(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-hexyl-pipe...)
Affinity DataKi:  0.5nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039819(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-hexyl-pipe...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataKi:  0.501nMAssay Description:Compound was tested for inhibition constant against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039805(1-Benzofuran-7-yl-4-hexyl-piperazine | CHEMBL27558)
Affinity DataKi:  0.540nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039805(1-Benzofuran-7-yl-4-hexyl-piperazine | CHEMBL27558)
Affinity DataKi:  0.540nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039796(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-octyl-pipe...)
Affinity DataKi:  0.610nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039796(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-octyl-pipe...)
Affinity DataKi:  0.610nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039814(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039814(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  0.676nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50470650(CHEMBL335401)
Affinity DataKi:  0.708nMAssay Description:Inhibition of [3H]2-(di-N-propylamino)-8-hydroxytetralin binding to 5-HT1A receptor of rat frontal cortex homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM85079(2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...)
Affinity DataKi:  0.708nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039807(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(2-phenoxy...)
Affinity DataKi:  0.730nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039795(1-Benzofuran-7-yl-4-pentyl-piperazine | CHEMBL2683...)
Affinity DataKi:  0.810nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039795(1-Benzofuran-7-yl-4-pentyl-piperazine | CHEMBL2683...)
Affinity DataKi:  0.810nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039802(1-Benzofuran-7-yl-4-(3-phenoxy-propyl)-piperazine;...)
Affinity DataKi:  0.850nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039827(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(3-phenoxy...)
Affinity DataKi:  0.950nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020180(4-(4-Benzofuran-7-yl-piperazin-1-yl)-1-(4-fluoro-p...)
Affinity DataKi:  1nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216215(CHEMBL81095)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039826(1-Decyl-4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-pipe...)
Affinity DataKi:  1nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039826(1-Decyl-4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-pipe...)
Affinity DataKi:  1nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50216214(CHEMBL311976)
Affinity DataKi:  1.20nMAssay Description:Compound was tested for its potency against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes (experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039811(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  1.30nMAssay Description:Compound was tested for its potency against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes (experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039811(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50454759(Flesinoxan)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039832(1-Benzofuran-7-yl-4-octyl-piperazine | CHEMBL26988)
Affinity DataKi:  1.70nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039832(1-Benzofuran-7-yl-4-octyl-piperazine | CHEMBL26988)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039806(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-pentyl-pip...)
Affinity DataKi:  2.20nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039806(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-pentyl-pip...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005135(1-(3-Chloro-phenyl)-4-hexyl-piperazine | CHEMBL279...)
Affinity DataKi:  2.70nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  2.80nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50470645(CHEMBL136494)
Affinity DataKi:  3.80nMAssay Description:Inhibition of [3H]2-(di-N-propylamino)-8-hydroxytetralin binding to 5-HT1A receptor of rat frontal cortex homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039792(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(2,3-dihyd...)
Affinity DataKi:  4nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50470647(CHEMBL135880)
Affinity DataKi:  4.70nMAssay Description:Inhibition of [3H]2-(di-N-propylamino)-8-hydroxytetralin binding to 5-HT1A receptor of rat frontal cortex homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50470653(CHEMBL135885)
Affinity DataKi:  4.80nMAssay Description:Inhibition of [3H]2-(di-N-propylamino)-8-hydroxytetralin binding to 5-HT1A receptor of rat frontal cortex homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005127(1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)
Affinity DataKi:  5.5nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005140(1-(3-Chloro-phenyl)-4-pentyl-piperazine | CHEMBL27...)
Affinity DataKi:  5.5nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate (experi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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