Affinity DataKi: 50nMAssay Description:Irreversible binding affinity to recombinant human PKM2 expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Binding affinity to PKM2 (unknown origin) assessed as oxidation of beta-NADH by spectrophotometry based LDH coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.16E+5nMAssay Description:Binding affinity to Leishmania mexicana PKMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+5nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-L)More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+6nMAssay Description:Inhibition of rat liver pyruvate kinase (PK-L) at 3.6 mMMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
Affinity DataKi: 3.70E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+6nMAssay Description:Inhibitory constant for inhibition of pyruvate kinase obtained from rat liver (PK-L) was determined using ADP as competitive inhibitorMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K) at 6.7 mMMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M) at 10 mMMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+6nMAssay Description:Inhibition of rat liver pyruvate kinase (PK-L); (relative inhibitory potency)More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M) at 6.7 mMMore data for this Ligand-Target Pair
Affinity DataKi: 5.40E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
Affinity DataKi: 7.00E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M) at 6.7 mMMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+6nMAssay Description:Inhibitory constant for inhibition of pyruvate kinase obtained from rat liver (PK-L) was determined using ADP as competitive inhibitorMore data for this Ligand-Target Pair
Affinity DataKi: 7.50E+6nMAssay Description:Inhibitory constant for inhibition of pyruvate kinase obtained from rat liver (PK-L) was determined using ADP as competitive inhibitorMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+6nMAssay Description:Michaelis-Menten constant for inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
Affinity DataKi: 8.40E+6nMAssay Description:Inhibitory constant for inhibition of pyruvate kinase obtained from rat liver (PK-L) was determined using ADP as competitive inhibitorMore data for this Ligand-Target Pair
Affinity DataKi: 9.30E+6nMAssay Description:Inhibition of rat muscle pyruvate kinase (PK-M)More data for this Ligand-Target Pair
Affinity DataKi: 1.09E+7nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K) at 6.7 mMMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+7nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus 252 pyruvate kinase by LDH assayMore data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus pyruvate kinase by coupled lactate dehydrogenase continuous assayMore data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus 252 pyruvate kinase by LDH assayMore data for this Ligand-Target Pair
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Simon Fraser University
Curated by ChEMBL
Simon Fraser University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus 252 pyruvate kinase by LDH assayMore data for this Ligand-Target Pair