Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 2917
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26059BDBM26059(5-nitro-2-[(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)sulf...)
Affinity DataIC50: 183nMpH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26058BDBM26058(5-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4-phenyl-4H...)
Affinity DataIC50: 237nMpH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26057BDBM26057(4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(5-nitro-1...)
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26057BDBM26057(4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(5-nitro-1...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26058BDBM26058(5-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4-phenyl-4H...)
Affinity DataIC50: 3.10E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26059BDBM26059(5-nitro-2-[(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)sulf...)
Affinity DataIC50: 3.30E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26060BDBM26060(4-methyl-2-[(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)sul...)
Affinity DataIC50: 7.50E+3nMpH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26061BDBM26061(5-(benzylsulfanyl)-1-phenyl-1H-1,2,3,4-tetrazole |...)
Affinity DataIC50: 2.50E+4nMpH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26062BDBM26062(4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(5-nitroth...)
Affinity DataIC50: 2.50E+4nMpH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26062BDBM26062(4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(5-nitroth...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26060BDBM26060(4-methyl-2-[(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)sul...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandChemical structure of BindingDB Monomer ID 26061BDBM26061(5-(benzylsulfanyl)-1-phenyl-1H-1,2,3,4-tetrazole |...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed