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Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for entry = 50001254   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM82087
PNG
(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Show SMILES COc1ccc2[nH]cc(CCN)c2c1
Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
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5n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014219
PNG
(2-(5-Methoxy-1H-indol-3-yl)-1-methyl-ethylamine | ...)
Show SMILES COc1ccc2[nH]cc(CC(C)N)c2c1
Show InChI InChI=1S/C12H16N2O/c1-8(13)5-9-7-14-12-4-3-10(15-2)6-11(9)12/h3-4,6-8,14H,5,13H2,1-2H3
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7n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50014218
PNG
(2-(5-Methoxy-1-propyl-1H-indol-3-yl)-1-methyl-ethy...)
Show SMILES CCCn1cc(CC(C)N)c2cc(OC)ccc12
Show InChI InChI=1S/C15H22N2O/c1-4-7-17-10-12(8-11(2)16)14-9-13(18-3)5-6-15(14)17/h5-6,9-11H,4,7-8,16H2,1-3H3
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12n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014212
PNG
(2-(1-Benzyl-5-methoxy-1H-indol-3-yl)-1-methyl-ethy...)
Show SMILES COc1ccc2n(Cc3ccccc3)cc(CC(C)N)c2c1
Show InChI InChI=1S/C19H22N2O/c1-14(20)10-16-13-21(12-15-6-4-3-5-7-15)19-9-8-17(22-2)11-18(16)19/h3-9,11,13-14H,10,12,20H2,1-2H3
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15n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014216
PNG
(2-(1-Benzyl-1H-indol-3-yl)-1-methyl-ethylamine | C...)
Show SMILES CC(N)Cc1cn(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C18H20N2/c1-14(19)11-16-13-20(12-15-7-3-2-4-8-15)18-10-6-5-9-17(16)18/h2-10,13-14H,11-12,19H2,1H3
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30n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014217
PNG
(1-Methyl-2-(1-octyl-1H-indol-3-yl)-ethylamine | CH...)
Show SMILES CCCCCCCCn1cc(CC(C)N)c2ccccc12
Show InChI InChI=1S/C19H30N2/c1-3-4-5-6-7-10-13-21-15-17(14-16(2)20)18-11-8-9-12-19(18)21/h8-9,11-12,15-16H,3-7,10,13-14,20H2,1-2H3
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78n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014221
PNG
(1-Methyl-2-(1-pentyl-1H-indol-3-yl)-ethylamine | C...)
Show SMILES CCCCCn1cc(CC(C)N)c2ccccc12
Show InChI InChI=1S/C16H24N2/c1-3-4-7-10-18-12-14(11-13(2)17)15-8-5-6-9-16(15)18/h5-6,8-9,12-13H,3-4,7,10-11,17H2,1-2H3
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100n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014214
PNG
(1-Methyl-2-(7-pentyl-1H-indol-3-yl)-ethylamine | C...)
Show SMILES CCCCCc1cccc2c(CC(C)N)c[nH]c12
Show InChI InChI=1S/C16H24N2/c1-3-4-5-7-13-8-6-9-15-14(10-12(2)17)11-18-16(13)15/h6,8-9,11-12,18H,3-5,7,10,17H2,1-2H3
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140n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014216
PNG
(2-(1-Benzyl-1H-indol-3-yl)-1-methyl-ethylamine | C...)
Show SMILES CC(N)Cc1cn(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C18H20N2/c1-14(19)11-16-13-20(12-15-7-3-2-4-8-15)18-10-6-5-9-17(16)18/h2-10,13-14H,11-12,19H2,1H3
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160n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014212
PNG
(2-(1-Benzyl-5-methoxy-1H-indol-3-yl)-1-methyl-ethy...)
Show SMILES COc1ccc2n(Cc3ccccc3)cc(CC(C)N)c2c1
Show InChI InChI=1S/C19H22N2O/c1-14(20)10-16-13-21(12-15-6-4-3-5-7-15)19-9-8-17(22-2)11-18(16)19/h3-9,11,13-14H,10,12,20H2,1-2H3
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250n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014217
PNG
(1-Methyl-2-(1-octyl-1H-indol-3-yl)-ethylamine | CH...)
Show SMILES CCCCCCCCn1cc(CC(C)N)c2ccccc12
Show InChI InChI=1S/C19H30N2/c1-3-4-5-6-7-10-13-21-15-17(14-16(2)20)18-11-8-9-12-19(18)21/h8-9,11-12,15-16H,3-7,10,13-14,20H2,1-2H3
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280n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM82087
PNG
(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Show SMILES COc1ccc2[nH]cc(CCN)c2c1
Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
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302n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014219
PNG
(2-(5-Methoxy-1H-indol-3-yl)-1-methyl-ethylamine | ...)
Show SMILES COc1ccc2[nH]cc(CC(C)N)c2c1
Show InChI InChI=1S/C12H16N2O/c1-8(13)5-9-7-14-12-4-3-10(15-2)6-11(9)12/h3-4,6-8,14H,5,13H2,1-2H3
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345n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014210
PNG
(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Show SMILES CC(N)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3
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530n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014218
PNG
(2-(5-Methoxy-1-propyl-1H-indol-3-yl)-1-methyl-ethy...)
Show SMILES CCCn1cc(CC(C)N)c2cc(OC)ccc12
Show InChI InChI=1S/C15H22N2O/c1-4-7-17-10-12(8-11(2)16)14-9-13(18-3)5-6-15(14)17/h5-6,9-11H,4,7-8,16H2,1-3H3
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635n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014222
PNG
(1-Methyl-2-(1-propyl-1H-indol-3-yl)-ethylamine | C...)
Show SMILES CCCn1cc(CC(C)N)c2ccccc12
Show InChI InChI=1S/C14H20N2/c1-3-8-16-10-12(9-11(2)15)13-6-4-5-7-14(13)16/h4-7,10-11H,3,8-9,15H2,1-2H3
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715n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014220
PNG
(1-Methyl-2-(7-propyl-1H-indol-3-yl)-ethylamine | C...)
Show SMILES CCCc1cccc2c(CC(C)N)c[nH]c12
Show InChI InChI=1S/C14H20N2/c1-3-5-11-6-4-7-13-12(8-10(2)15)9-16-14(11)13/h4,6-7,9-10,16H,3,5,8,15H2,1-2H3
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1.00E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014220
PNG
(1-Methyl-2-(7-propyl-1H-indol-3-yl)-ethylamine | C...)
Show SMILES CCCc1cccc2c(CC(C)N)c[nH]c12
Show InChI InChI=1S/C14H20N2/c1-3-5-11-6-4-7-13-12(8-10(2)15)9-16-14(11)13/h4,6-7,9-10,16H,3,5,8,15H2,1-2H3
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1.04E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014222
PNG
(1-Methyl-2-(1-propyl-1H-indol-3-yl)-ethylamine | C...)
Show SMILES CCCn1cc(CC(C)N)c2ccccc12
Show InChI InChI=1S/C14H20N2/c1-3-8-16-10-12(9-11(2)15)13-6-4-5-7-14(13)16/h4-7,10-11H,3,8-9,15H2,1-2H3
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1.55E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014221
PNG
(1-Methyl-2-(1-pentyl-1H-indol-3-yl)-ethylamine | C...)
Show SMILES CCCCCn1cc(CC(C)N)c2ccccc12
Show InChI InChI=1S/C16H24N2/c1-3-4-7-10-18-12-14(11-13(2)17)15-8-5-6-9-16(15)18/h5-6,8-9,12-13H,3-4,7,10-11,17H2,1-2H3
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2.40E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014223
PNG
(1-Methyl-2-(1-pentyl-1H-pyrrol-3-yl)-ethylamine | ...)
Show SMILES CCCCCn1ccc(CC(C)N)c1
Show InChI InChI=1S/C12H22N2/c1-3-4-5-7-14-8-6-12(10-14)9-11(2)13/h6,8,10-11H,3-5,7,9,13H2,1-2H3
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5.20E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014214
PNG
(1-Methyl-2-(7-pentyl-1H-indol-3-yl)-ethylamine | C...)
Show SMILES CCCCCc1cccc2c(CC(C)N)c[nH]c12
Show InChI InChI=1S/C16H24N2/c1-3-4-5-7-13-8-6-9-15-14(10-12(2)17)11-18-16(13)15/h6,8-9,11-12,18H,3-5,7,10,17H2,1-2H3
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6.85E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014218
PNG
(2-(5-Methoxy-1-propyl-1H-indol-3-yl)-1-methyl-ethy...)
Show SMILES CCCn1cc(CC(C)N)c2cc(OC)ccc12
Show InChI InChI=1S/C15H22N2O/c1-4-7-17-10-12(8-11(2)16)14-9-13(18-3)5-6-15(14)17/h5-6,9-11H,4,7-8,16H2,1-3H3
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7.10E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014223
PNG
(1-Methyl-2-(1-pentyl-1H-pyrrol-3-yl)-ethylamine | ...)
Show SMILES CCCCCn1ccc(CC(C)N)c1
Show InChI InChI=1S/C12H22N2/c1-3-4-5-7-14-8-6-12(10-14)9-11(2)13/h6,8,10-11H,3-5,7,9,13H2,1-2H3
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7.50E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50014212
PNG
(2-(1-Benzyl-5-methoxy-1H-indol-3-yl)-1-methyl-ethy...)
Show SMILES COc1ccc2n(Cc3ccccc3)cc(CC(C)N)c2c1
Show InChI InChI=1S/C19H22N2O/c1-14(20)10-16-13-21(12-15-6-4-3-5-7-15)19-9-8-17(22-2)11-18(16)19/h3-9,11,13-14H,10,12,20H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014211
PNG
(1-Methyl-2-(1-propyl-1H-pyrrol-3-yl)-ethylamine | ...)
Show SMILES CCCn1ccc(CC(C)N)c1
Show InChI InChI=1S/C10H18N2/c1-3-5-12-6-4-10(8-12)7-9(2)11/h4,6,8-9H,3,5,7,11H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014210
PNG
(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Show SMILES CC(N)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014215
PNG
(1-Methyl-2-(1H-pyrrol-3-yl)-ethylamine | CHEMBL328...)
Show SMILES CC(N)Cc1cc[nH]c1
Show InChI InChI=1S/C7H12N2/c1-6(8)4-7-2-3-9-5-7/h2-3,5-6,9H,4,8H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50014211
PNG
(1-Methyl-2-(1-propyl-1H-pyrrol-3-yl)-ethylamine | ...)
Show SMILES CCCn1ccc(CC(C)N)c1
Show InChI InChI=1S/C10H18N2/c1-3-5-12-6-4-10(8-12)7-9(2)11/h4,6,8-9H,3,5,7,11H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50014215
PNG
(1-Methyl-2-(1H-pyrrol-3-yl)-ethylamine | CHEMBL328...)
Show SMILES CC(N)Cc1cc[nH]c1
Show InChI InChI=1S/C7H12N2/c1-6(8)4-7-2-3-9-5-7/h2-3,5-6,9H,4,8H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand


J Med Chem 33: 2777-84 (1990)


Article DOI: 10.1021/jm00172a016
BindingDB Entry DOI: 10.7270/Q2GX49JP
More data for this
Ligand-Target Pair