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Compile Data Set for Download or QSAR

Found 32 hits Enz. Inhib. hit(s) with all data for entry = 50005207   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034281
PNG
(Bicyclo[2.2.1]heptane-2-carboxylic acid {2-[4-(2-m...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CC3CCC2C3)CC1
Show InChI InChI=1S/C21H31N3O2/c1-26-20-5-3-2-4-19(20)24-12-10-23(11-13-24)9-8-22-21(25)18-15-16-6-7-17(18)14-16/h2-5,16-18H,6-15H2,1H3,(H,22,25)
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0.120n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034308
PNG
(Bicyclo[2.2.1]heptane-2-carboxylic acid {4-[4-(2-m...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C2CC3CCC2C3)CC1
Show InChI InChI=1S/C23H35N3O2/c1-28-22-7-3-2-6-21(22)26-14-12-25(13-15-26)11-5-4-10-24-23(27)20-17-18-8-9-19(20)16-18/h2-3,6-7,18-20H,4-5,8-17H2,1H3,(H,24,27)
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0.230n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034292
PNG
(CHEMBL25654 | Octahydro-pentalene-2-carboxylic aci...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CC3CCCC3C2)CC1
Show InChI InChI=1S/C22H33N3O2/c1-27-21-8-3-2-7-20(21)25-13-11-24(12-14-25)10-9-23-22(26)19-15-17-5-4-6-18(17)16-19/h2-3,7-8,17-19H,4-6,9-16H2,1H3,(H,23,26)
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0.240n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034300
PNG
(Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid {2-[4-(...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CC3CC2C=C3)CC1
Show InChI InChI=1S/C21H29N3O2/c1-26-20-5-3-2-4-19(20)24-12-10-23(11-13-24)9-8-22-21(25)18-15-16-6-7-17(18)14-16/h2-7,16-18H,8-15H2,1H3,(H,22,25)
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0.270n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034303
PNG
(Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid {4-[4-(...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C2CC3CC2C=C3)CC1
Show InChI InChI=1S/C23H33N3O2/c1-28-22-7-3-2-6-21(22)26-14-12-25(13-15-26)11-5-4-10-24-23(27)20-17-18-8-9-19(20)16-18/h2-3,6-9,18-20H,4-5,10-17H2,1H3,(H,24,27)
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0.380n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034302
PNG
(CHEMBL23877 | Octahydro-pentalene-2-carboxylic aci...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C2CC3CCCC3C2)CC1
Show InChI InChI=1S/C24H37N3O2/c1-29-23-10-3-2-9-22(23)27-15-13-26(14-16-27)12-5-4-11-25-24(28)21-17-19-7-6-8-20(19)18-21/h2-3,9-10,19-21H,4-8,11-18H2,1H3,(H,25,28)
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0.630n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034296
PNG
(1-Methyl-1H-pyrrole-2-carboxylic acid {4-[4-(2-met...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccn2C)CC1
Show InChI InChI=1S/C21H30N4O2/c1-23-12-7-9-19(23)21(26)22-11-5-6-13-24-14-16-25(17-15-24)18-8-3-4-10-20(18)27-2/h3-4,7-10,12H,5-6,11,13-17H2,1-2H3,(H,22,26)
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0.740n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
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1.18n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034288
PNG
(1-Methyl-1H-pyrrole-2-carboxylic acid {2-[4-(2-met...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2cccn2C)CC1
Show InChI InChI=1S/C19H26N4O2/c1-21-10-5-7-17(21)19(24)20-9-11-22-12-14-23(15-13-22)16-6-3-4-8-18(16)25-2/h3-8,10H,9,11-15H2,1-2H3,(H,20,24)
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1.19n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM82517
PNG
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
Show InChI InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3
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1.26n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034309
PNG
(3-Methyl-thiophene-2-carboxylic acid {4-[4-(2-meth...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2sccc2C)CC1
Show InChI InChI=1S/C21H29N3O2S/c1-17-9-16-27-20(17)21(25)22-10-5-6-11-23-12-14-24(15-13-23)18-7-3-4-8-19(18)26-2/h3-4,7-9,16H,5-6,10-15H2,1-2H3,(H,22,25)
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1.53n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034286
PNG
(CHEMBL23904 | Cyclopentanecarboxylic acid {4-[4-(2...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)C2CCCC2)CC1
Show InChI InChI=1S/C21H33N3O2/c1-26-20-11-5-4-10-19(20)24-16-14-23(15-17-24)13-7-6-12-22-21(25)18-8-2-3-9-18/h4-5,10-11,18H,2-3,6-9,12-17H2,1H3,(H,22,25)
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1.88n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034282
PNG
(CHEMBL282012 | Thiophene-3-carboxylic acid {4-[4-(...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccsc2)CC1
Show InChI InChI=1S/C20H27N3O2S/c1-25-19-7-3-2-6-18(19)23-13-11-22(12-14-23)10-5-4-9-21-20(24)17-8-15-26-16-17/h2-3,6-8,15-16H,4-5,9-14H2,1H3,(H,21,24)
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2.20n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034304
PNG
(5-Methyl-thiophene-2-carboxylic acid {2-[4-(2-meth...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2ccc(C)s2)CC1
Show InChI InChI=1S/C19H25N3O2S/c1-15-7-8-18(25-15)19(23)20-9-10-21-11-13-22(14-12-21)16-5-3-4-6-17(16)24-2/h3-8H,9-14H2,1-2H3,(H,20,23)
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2.29n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034284
PNG
(CHEMBL23449 | Thiophene-2-carboxylic acid {4-[4-(2...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccs2)CC1
Show InChI InChI=1S/C20H27N3O2S/c1-25-18-8-3-2-7-17(18)23-14-12-22(13-15-23)11-5-4-10-21-20(24)19-9-6-16-26-19/h2-3,6-9,16H,4-5,10-15H2,1H3,(H,21,24)
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2.34n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034298
PNG
(3-Methyl-thiophene-2-carboxylic acid {2-[4-(2-meth...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2sccc2C)CC1
Show InChI InChI=1S/C19H25N3O2S/c1-15-7-14-25-18(15)19(23)20-8-9-21-10-12-22(13-11-21)16-5-3-4-6-17(16)24-2/h3-7,14H,8-13H2,1-2H3,(H,20,23)
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3.09n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034301
PNG
(3-Chloro-thiophene-2-carboxylic acid {4-[4-(2-meth...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2sccc2Cl)CC1
Show InChI InChI=1S/C20H26ClN3O2S/c1-26-18-7-3-2-6-17(18)24-13-11-23(12-14-24)10-5-4-9-22-20(25)19-16(21)8-15-27-19/h2-3,6-8,15H,4-5,9-14H2,1H3,(H,22,25)
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3.34n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034297
PNG
(5-Methyl-thiophene-2-carboxylic acid {4-[4-(2-meth...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(C)s2)CC1
Show InChI InChI=1S/C21H29N3O2S/c1-17-9-10-20(27-17)21(25)22-11-5-6-12-23-13-15-24(16-14-23)18-7-3-4-8-19(18)26-2/h3-4,7-10H,5-6,11-16H2,1-2H3,(H,22,25)
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3.80n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034295
PNG
(CHEMBL23905 | Cyclopentanecarboxylic acid {2-[4-(2...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CCCC2)CC1
Show InChI InChI=1S/C19H29N3O2/c1-24-18-9-5-4-8-17(18)22-14-12-21(13-15-22)11-10-20-19(23)16-6-2-3-7-16/h4-5,8-9,16H,2-3,6-7,10-15H2,1H3,(H,20,23)
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4.68n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034299
PNG
(CHEMBL276953 | Thiophene-3-carboxylic acid {2-[4-(...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2ccsc2)CC1
Show InChI InChI=1S/C18H23N3O2S/c1-23-17-5-3-2-4-16(17)21-11-9-20(10-12-21)8-7-19-18(22)15-6-13-24-14-15/h2-6,13-14H,7-12H2,1H3,(H,19,22)
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6.83n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034290
PNG
(CHEMBL280426 | Octahydro-pentalene-2-carboxylic ac...)
Show SMILES COc1ccccc1N1CCN(CCCNC(=O)C2CC3CCCC3C2)CC1
Show InChI InChI=1S/C23H35N3O2/c1-28-22-9-3-2-8-21(22)26-14-12-25(13-15-26)11-5-10-24-23(27)20-16-18-6-4-7-19(18)17-20/h2-3,8-9,18-20H,4-7,10-17H2,1H3,(H,24,27)
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11.6n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034306
PNG
(1H-Pyrrole-2-carboxylic acid {4-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc[nH]2)CC1
Show InChI InChI=1S/C20H28N4O2/c1-26-19-9-3-2-8-18(19)24-15-13-23(14-16-24)12-5-4-10-22-20(25)17-7-6-11-21-17/h2-3,6-9,11,21H,4-5,10,12-16H2,1H3,(H,22,25)
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12.5n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50001859
PNG
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
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15.4n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034291
PNG
(CHEMBL22872 | N-{4-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)Cc2ccsc2)CC1
Show InChI InChI=1S/C21H29N3O2S/c1-26-20-7-3-2-6-19(20)24-13-11-23(12-14-24)10-5-4-9-22-21(25)16-18-8-15-27-17-18/h2-3,6-8,15,17H,4-5,9-14,16H2,1H3,(H,22,25)
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17.5n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034285
PNG
(1H-Pyrrole-2-carboxylic acid {2-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2ccc[nH]2)CC1
Show InChI InChI=1S/C18H24N4O2/c1-24-17-7-3-2-6-16(17)22-13-11-21(12-14-22)10-9-20-18(23)15-5-4-8-19-15/h2-8,19H,9-14H2,1H3,(H,20,23)
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20.3n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034307
PNG
(CHEMBL23912 | N-{4-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccnc2)CC1
Show InChI InChI=1S/C21H28N4O2/c1-27-20-9-3-2-8-19(20)25-15-13-24(14-16-25)12-5-4-11-23-21(26)18-7-6-10-22-17-18/h2-3,6-10,17H,4-5,11-16H2,1H3,(H,23,26)
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25.2n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034294
PNG
(3-Methoxy-thiophene-2-carboxylic acid {4-[4-(2-met...)
Show SMILES COc1ccsc1C(=O)NCCCCN1CCN(CC1)c1ccccc1OC
Show InChI InChI=1S/C21H29N3O3S/c1-26-18-8-4-3-7-17(18)24-14-12-23(13-15-24)11-6-5-10-22-21(25)20-19(27-2)9-16-28-20/h3-4,7-9,16H,5-6,10-15H2,1-2H3,(H,22,25)
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32.1n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034293
PNG
(CHEMBL23817 | N-{2-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)Cc2ccsc2)CC1
Show InChI InChI=1S/C19H25N3O2S/c1-24-18-5-3-2-4-17(18)22-11-9-21(10-12-22)8-7-20-19(23)14-16-6-13-25-15-16/h2-6,13,15H,7-12,14H2,1H3,(H,20,23)
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32.3n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034289
PNG
(CHEMBL442065 | Furan-2-carboxylic acid {4-[4-(2-me...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccco2)CC1
Show InChI InChI=1S/C20H27N3O3/c1-25-18-8-3-2-7-17(18)23-14-12-22(13-15-23)11-5-4-10-21-20(24)19-9-6-16-26-19/h2-3,6-9,16H,4-5,10-15H2,1H3,(H,21,24)
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55.7n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034287
PNG
(1H-Pyrrole-2-carboxylic acid {3-[4-(2-methoxy-phen...)
Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2ccc[nH]2)CC1
Show InChI InChI=1S/C19H26N4O2/c1-25-18-8-3-2-7-17(18)23-14-12-22(13-15-23)11-5-10-21-19(24)16-6-4-9-20-16/h2-4,6-9,20H,5,10-15H2,1H3,(H,21,24)
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201n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034305
PNG
(CHEMBL24113 | N-{3-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cccnc2)CC1
Show InChI InChI=1S/C20H26N4O2/c1-26-19-8-3-2-7-18(19)24-14-12-23(13-15-24)11-5-10-22-20(25)17-6-4-9-21-16-17/h2-4,6-9,16H,5,10-15H2,1H3,(H,22,25)
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321n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034283
PNG
(CHEMBL26447 | N-{2-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2cccnc2)CC1
Show InChI InChI=1S/C19H24N4O2/c1-25-18-7-3-2-6-17(18)23-13-11-22(12-14-23)10-9-21-19(24)16-5-4-8-20-15-16/h2-8,15H,9-14H2,1H3,(H,21,24)
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362n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair