BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with all data for entry = 50032123   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-lactamase AmpC


(Escherichia coli)
BDBM50324682
PNG
(3-(N-(4-carboxy-2-hydroxyphenyl)sulfamoyl)thiophen...)
Show SMILES OC(=O)c1sccc1S(=O)(=O)Nc1ccc(cc1O)C(O)=O
Show InChI InChI=1S/C12H9NO7S2/c14-8-5-6(11(15)16)1-2-7(8)13-22(19,20)9-3-4-21-10(9)12(17)18/h1-5,13-14H,(H,15,16)(H,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
MMDB
PDB
Article
PubMed
1.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli AmpC assessed as nitrocefin hydrolysis by UV-Vis spectrophotometry


Nat Chem Biol 2: 720-3 (2006)


Article DOI: 10.1038/nchembio831
BindingDB Entry DOI: 10.7270/Q2FN16DF
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta-lactamase AmpC


(Escherichia coli)
BDBM50324679
PNG
(2-(ACETYLAMINO)THIOPHENE-3-CARBOXYLIC ACID | 2-ace...)
Show SMILES CC(=O)Nc1sccc1C(O)=O
Show InChI InChI=1S/C7H7NO3S/c1-4(9)8-6-5(7(10)11)2-3-12-6/h2-3H,1H3,(H,8,9)(H,10,11)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

MMDB
PDB
Article
PubMed
5.00E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli AmpC assessed as nitrocefin hydrolysis by UV-Vis spectrophotometry


Nat Chem Biol 2: 720-3 (2006)


Article DOI: 10.1038/nchembio831
BindingDB Entry DOI: 10.7270/Q2FN16DF
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta-lactamase AmpC


(Escherichia coli)
BDBM50324680
PNG
(4-(methylsulfonamido)benzoic acid | 4-Methanesulfo...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(O)=O
Show InChI InChI=1S/C8H9NO4S/c1-14(12,13)9-7-4-2-6(3-5-7)8(10)11/h2-5,9H,1H3,(H,10,11)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents

MMDB
PDB
Article
PubMed
1.00E+7n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli AmpC assessed as nitrocefin hydrolysis by UV-Vis spectrophotometry


Nat Chem Biol 2: 720-3 (2006)


Article DOI: 10.1038/nchembio831
BindingDB Entry DOI: 10.7270/Q2FN16DF
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta-lactamase AmpC


(Escherichia coli)
BDBM50324681
PNG
(4-AMINO-3-HYDROXYBENZOIC ACID | CHEMBL1462)
Show SMILES Nc1ccc(cc1O)C(O)=O
Show InChI InChI=1S/C7H7NO3/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,9H,8H2,(H,10,11)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

MMDB
PDB
Article
PubMed
1.90E+7n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli AmpC assessed as nitrocefin hydrolysis by UV-Vis spectrophotometry


Nat Chem Biol 2: 720-3 (2006)


Article DOI: 10.1038/nchembio831
BindingDB Entry DOI: 10.7270/Q2FN16DF
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta-lactamase AmpC


(Escherichia coli)
BDBM50324678
PNG
(CHEMBL1222314 | thiophene-2-carboxylic acid)
Show SMILES OC(=O)c1cccs1
Show InChI InChI=1S/C5H4O2S/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEBI
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents

MMDB
PDB
Article
PubMed
4.00E+7n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli AmpC assessed as nitrocefin hydrolysis by UV-Vis spectrophotometry


Nat Chem Biol 2: 720-3 (2006)


Article DOI: 10.1038/nchembio831
BindingDB Entry DOI: 10.7270/Q2FN16DF
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)