BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with all data for entry = 50035706   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50405614
PNG
(CHEMBL1178569)
Show SMILES N[C@H]1CCc2ccccc2C1
Show InChI InChI=1S/C10H13N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-4,10H,5-7,11H2/t10-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.10E+3n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro binding affinity of compound towards bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)


J Med Chem 31: 1984-6 (1988)


Article DOI: 10.1021/jm00118a021
BindingDB Entry DOI: 10.7270/Q2QF8TFD
More data for this
Ligand-Target Pair
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50023139
PNG
(2-Amino-1,2,3,4-tetrahydro-naphthalen-1-ol | CHEMB...)
Show SMILES N[C@H]1CCc2ccccc2[C@@H]1O
Show InChI InChI=1S/C10H13NO/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-4,9-10,12H,5-6,11H2/t9-,10-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
4.60E+3n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro binding affinity of compound towards bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)


J Med Chem 31: 1984-6 (1988)


Article DOI: 10.1021/jm00118a021
BindingDB Entry DOI: 10.7270/Q2QF8TFD
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50405616
PNG
(CHEMBL2114376)
Show SMILES N[C@@H]1CCc2ccccc2C1
Show InChI InChI=1S/C10H13N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-4,10H,5-7,11H2/t10-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.00E+4n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro binding affinity of compound towards bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)


J Med Chem 31: 1984-6 (1988)


Article DOI: 10.1021/jm00118a021
BindingDB Entry DOI: 10.7270/Q2QF8TFD
More data for this
Ligand-Target Pair
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50405612
PNG
(CHEMBL2051934)
Show SMILES N[C@@H]1CCc2ccccc2[C@@H]1O
Show InChI InChI=1S/C10H13NO/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-4,9-10,12H,5-6,11H2/t9-,10+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.93E+5n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro binding affinity of compound towards bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)


J Med Chem 31: 1984-6 (1988)


Article DOI: 10.1021/jm00118a021
BindingDB Entry DOI: 10.7270/Q2QF8TFD
More data for this
Ligand-Target Pair
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50022723
PNG
((+)-(S)-amphetamine | (+)-alpha-methylphenethylami...)
Show SMILES C[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
4.22E+5n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro binding affinity of compound towards bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)


J Med Chem 31: 1984-6 (1988)


Article DOI: 10.1021/jm00118a021
BindingDB Entry DOI: 10.7270/Q2QF8TFD
More data for this
Ligand-Target Pair
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50022721
PNG
((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Show SMILES C[C@@H](N)Cc1ccccc1
Show InChI InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
1.38E+6n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro binding affinity of compound towards bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)


J Med Chem 31: 1984-6 (1988)


Article DOI: 10.1021/jm00118a021
BindingDB Entry DOI: 10.7270/Q2QF8TFD
More data for this
Ligand-Target Pair
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50367603
PNG
(CHEMBL1788114)
Show SMILES C[C@@H](N)[C@H](O)c1ccccc1
Show InChI InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
2.44E+6n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro binding affinity of compound towards bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)


J Med Chem 31: 1984-6 (1988)


Article DOI: 10.1021/jm00118a021
BindingDB Entry DOI: 10.7270/Q2QF8TFD
More data for this
Ligand-Target Pair
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50405613
PNG
(PHENYLPROPANOLAMINE)
Show SMILES C[C@@H](N)[C@@H](O)c1ccccc1
Show InChI InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

DrugBank
KEGG
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
2.98E+6n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro binding affinity of compound towards bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)


J Med Chem 31: 1984-6 (1988)


Article DOI: 10.1021/jm00118a021
BindingDB Entry DOI: 10.7270/Q2QF8TFD
More data for this
Ligand-Target Pair
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50405615
PNG
(CATHINE)
Show SMILES C[C@H](N)[C@@H](O)c1ccccc1
Show InChI InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

DrugBank
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.70E+6n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro binding affinity of compound towards bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)


J Med Chem 31: 1984-6 (1988)


Article DOI: 10.1021/jm00118a021
BindingDB Entry DOI: 10.7270/Q2QF8TFD
More data for this
Ligand-Target Pair