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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 189080   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM189080
PNG
(US9169260, 349)
Show SMILES CN(C)C(=O)c1ccc(cc1)-c1cc(NC(=O)c2cnn3cccnc23)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C26H23N7O2/c1-17-5-11-20(12-6-17)33-23(29-25(34)21-16-28-32-14-4-13-27-24(21)32)15-22(30-33)18-7-9-19(10-8-18)26(35)31(2)3/h4-16H,1-3H3,(H,29,34)
PDB
MMDB

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Similars

US Patent
n/an/a<100n/an/an/an/a7.2n/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
The kinase activity of IRAK-4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phos...


US Patent US9169260 (2015)


BindingDB Entry DOI: 10.7270/Q26H4G6N
More data for this
Ligand-Target Pair