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Found 5 of ic50 for monomerid = 50329311
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329311((R)-3-(5-Trifluoromethyl-pyridin-2-ylamino)-pyrrol...)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of recombinant 11betaHSD1 expressed in CHO cells assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329311((R)-3-(5-Trifluoromethyl-pyridin-2-ylamino)-pyrrol...)
Affinity DataIC50:  5nMAssay Description:Inhibition of 11betaHSD1 in human platelet assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329311((R)-3-(5-Trifluoromethyl-pyridin-2-ylamino)-pyrrol...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329311((R)-3-(5-Trifluoromethyl-pyridin-2-ylamino)-pyrrol...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329311((R)-3-(5-Trifluoromethyl-pyridin-2-ylamino)-pyrrol...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed