Affinity DataKi: 6.10nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Compound was evaluated for the binding affinity at 5- HT2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 14.3nMAssay Description:Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Binding affinity towards Serotonin 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Compound was evaluated for the binding affinity at Alpha adrenergic receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical
Curated by ChEMBL
Dainippon Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 94.7nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical
Curated by ChEMBL
Dainippon Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 134nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical
Curated by ChEMBL
Dainippon Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 134nMAssay Description:Displacement of [3H]GR65630 from 5HT3 receptor in brain cortex from Wistar ratMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Paris-Sud University
Curated by ChEMBL
Paris-Sud University
Curated by ChEMBL
Affinity DataKi: 152nMAssay Description:Compound was tested for 5-hydroxytryptamine 3 receptor binding affinityMore data for this Ligand-Target Pair
Affinity DataKi: 227nMAssay Description:Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 227nMAssay Description:The ability to inhibit [3H]domperidone binding to dopamine receptor D2 in rat striataMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Compound was evaluated in vivo for the antagonistic activity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striataMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair