Found 31 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50001885' Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 130nMAssay Description:Ability to displace [3H]-8-OH-DPAT from serotonergic 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 171nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 182nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 182nMAssay Description:Displacement of [3H](+)8-OH-DPAT from rat cerebral cortex 5HT1A receptor measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 182nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 182nMAssay Description:Displacement of [3H]-8-OH-DPAT from serotonin 5-HT1A receptor in rat brain cortex homogenates incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 190nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptor in CRL:CD(SD)BR-COBS rat hippocampus by scintillation spectrometryMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Binding affinity to human cloned 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 211nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in rat cerebral cortex homogenates after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 251nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 253nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor determined using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 253nMAssay Description:Compound was evaluated for its binding affinity with 5-hydroxytryptamine 1A receptor using membranes prepared from rat cerebral cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 271nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 491nMAssay Description:Binding affinity measured at the 5-hydroxytryptamine 1A receptor by the inhibition of [3H]-8-OH-DPAT binding to rat cortex using unlabeled buspirone ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataKi: 720nMAssay Description:The compound was tested binding affinity against 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand at 10e-6 M.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.17E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1AR expressed in HEK293 cell membranes after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataIC50: 820nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissueMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataIC50: 950nMAssay Description:In vitro affinity towards 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in hippocampusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck
Curated by PDSP Ki Database
H. Lundbeck
Curated by PDSP Ki Database
Affinity DataIC50: 950nMAssay Description:Binding affinity towards serotonin 5-HT1A receptor was determined in rat hippocampus using [3H]8-OH-DPAT as ligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at 5-HT1A receptor (unknown origin) after 60 mins by Ultra lance cAMP assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:The 5-HT1A receptor agonism activity test (The agonism activity of test compounds on 5-HT1A receptor expressing human recombinant 5-HT1A receptor in ...More data for this Ligand-Target Pair
