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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiotensin II receptor' and Ligand = 'BDBM50230906'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50230906
PNG
(CHEMBL308261)
Show SMILES CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1)-n1c(Cl)ccc1Cl
Show InChI InChI=1S/C25H21Cl2N7O2/c1-2-5-21-28-24(34-19(26)12-13-20(34)27)22(25(35)36)33(21)14-15-8-10-16(11-9-15)17-6-3-4-7-18(17)23-29-31-32-30-23/h3-4,6-13H,2,5,14H2,1H3,(H,35,36)(H,29,30,31,32)
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Similars

Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against [125I]angiotensin II(AII) induced contraction in rabbit aorta by 50%


J Med Chem 36: 2253-65 (1993)


Article DOI: 10.1021/jm00068a002
More data for this
Ligand-Target Pair