Found 16 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50012632' 
Affinity DataIC50: 126nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 173nMAssay Description:Inhibition of BACE 1 (unknown origin) using 250 nM of Rh-EVNLDAEFK-Quencher as substrate after 1 hr by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 239nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 239nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
Affinity DataIC50: 239nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of IgG1 Fc-fused human recombinant BACE1 (1 to 460 residues) expressed in HEK293 cells using methylcoumarin peptide harboring Swedish muta...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human BACE1 by 7-methoxycoumarin-4-yl-acetyl-based FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human BACE-1More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of BACE1 (unknown origin) using beta-secretase as substrate incubated in dark for 1 hr by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 269nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using Rh-EVNLDAEFK-quencher as substrate measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant BACE1 using MBP-C125Swe as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of BACE1 in human H4 cells expressing APP751 Swedish mutant assessed as inhibition of amyloid beta 40 or amyloid beta 42 production incuba...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of BACE-1 in HEK293 cells expressing human APP751 cDNA harboring N670L671 mutation pretreated for 2 hrs followed by measuring after 2 hrs ...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of human BACE1 using MOCA-SEV-NL-DAEFR-DNP-RR as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APPswedish mutant assessed as inhibition of amyloid beta production by ELISAMore data for this Ligand-Target Pair
