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Found 3 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50322915'
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322915(3-(ethylsulfonyl)-N-((2S,3R)-3-hydroxy-1-phenyl-4-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322915(3-(ethylsulfonyl)-N-((2S,3R)-3-hydroxy-1-phenyl-4-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322915(3-(ethylsulfonyl)-N-((2S,3R)-3-hydroxy-1-phenyl-4-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed