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Found 4 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50440736'
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50440736(CHEMBL2431088)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of BRD4 bromodomain-1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50440736(CHEMBL2431088)
Affinity DataIC50:  2.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50440736(CHEMBL2431088)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50440736(CHEMBL2431088)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of BRD4 (unknown origin) expressed in Escherichia coli BL21 (DE3) using [Lys(Ac)5/8/12/16]-histone H4 (1 to 21residues)-GGK as substrate i...More data for this Ligand-Target Pair