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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Casein kinase I delta/epsilon' and Ligand = 'BDBM274628'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase I delta/epsilon


(Homo sapiens (Human))
BDBM274628
PNG
(6-(tert-butyl)-N-(6-(2-(4- fluorophenyl)imidazo[1,...)
Show SMILES CC(C)(C)c1cc(ncn1)C(=O)Nc1cn2nc(ccc2n1)-c1c(nc2ccccn12)-c1ccc(F)cc1
Show InChI InChI=1S/C28H23FN8O/c1-28(2,3)21-14-20(30-16-31-21)27(38)33-22-15-37-24(32-22)12-11-19(35-37)26-25(17-7-9-18(29)10-8-17)34-23-6-4-5-13-36(23)26/h4-16H,1-3H3,(H,33,38)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 9.84n/an/an/an/a7.425



Bristol-Myers Squibb Co.

US Patent


Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...


US Patent US9556179 (2017)


BindingDB Entry DOI: 10.7270/Q2G73GR5
More data for this
Ligand-Target Pair