Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM179867'
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179867(US11147820, Compound Metopimazine | US9132134, Met...)
Affinity DataKi:  0.0700nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179867(US11147820, Compound Metopimazine | US9132134, Met...)
Affinity DataKi:  0.0700nMAssay Description:For the radioligand binding assay, cell membranes of dopamine D2 receptor expressing cells were incubated with [3H]spiperone and competing drugs in b...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179867(US11147820, Compound Metopimazine | US9132134, Met...)
Affinity DataIC50:  2.20nMAssay Description:The functional antagonist assay was performed as described in Payne, S. L et al. (2002) J. Neurochem., 82: 1106-1117, hereby incorporated by referenc...More data for this Ligand-Target Pair
In DepthDetails US Patent