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Found 7 Enz. Inhib. hit(s) with Target = 'D-amino-acid oxidase' and Ligand = 'BDBM196661'
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196661(US10202399, Example 21 | US10463663, Example 17 | ...)
Affinity DataIC50:  2.20nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196661(US10202399, Example 21 | US10463663, Example 17 | ...)
Affinity DataIC50:  2.20nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196661(US10202399, Example 21 | US10463663, Example 17 | ...)
Affinity DataIC50:  5.5nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196661(US10202399, Example 21 | US10463663, Example 17 | ...)
Affinity DataIC50:  13nMpH: 7.4 T: 2°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196661(US10202399, Example 21 | US10463663, Example 17 | ...)
Affinity DataIC50:  13nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196661(US10202399, Example 21 | US10463663, Example 17 | ...)
Affinity DataIC50:  13nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196661(US10202399, Example 21 | US10463663, Example 17 | ...)
Affinity DataIC50:  13nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent