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Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50177858'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50177858(CHEMBL3814859)
Affinity DataEC50:  3.38E+3nMAssay Description:Inhibitory activity towards acetylcholine esterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50177858(CHEMBL3814859)
Affinity DataEC50:  550nMAssay Description:Inhibition of EGFR T790M/L858R double mutant autophosphorylation in human NCI-H1975 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50177858(CHEMBL3814859)
Affinity DataEC50:  120nMAssay Description:Inhibition of EGFR exon19 deletion activating mutant autophosphorylation in human PC9 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed