Found 1 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase, H3 lysine-79 specific' and Ligand = 'BDBM297393' TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Epizyme
US Patent
Epizyme
US Patent
Affinity DataKi: 845nM Kd: 167nM Kon: 0.200M-1s-1 Koff: 1.20E+6s-1Assay Description:Unless otherwise indicated, assays of DOT1L enzymatic activity were performed under balanced conditions (all substrates present at concentrations equ...More data for this Ligand-Target Pair
