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Found 4 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50171151'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50171151((2S,4aS,6aR,7R,9S,10aS,10bR)-9-acetoxy-2-(furan-3-...)
Affinity DataKi:  48.6nMAssay Description:Displacement of [3H]diprenorphine binding from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50171151((2S,4aS,6aR,7R,9S,10aS,10bR)-9-acetoxy-2-(furan-3-...)
Affinity DataKi:  49nMAssay Description:Binding affinity for 1 uM [3H]-diprenorphine against human Opioid receptor kappa expressed in chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50171151((2S,4aS,6aR,7R,9S,10aS,10bR)-9-acetoxy-2-(furan-3-...)
Affinity DataEC50:  74nMAssay Description:Concentration required to enhance [35S]-GTP-gammaS, binding to human Opioid receptor kappa expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50171151((2S,4aS,6aR,7R,9S,10aS,10bR)-9-acetoxy-2-(furan-3-...)
Affinity DataEC50:  74.1nMAssay Description:Binding potency at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed