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Found 4 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 6B' and Ligand = 'BDBM26113'
TargetLysine-specific demethylase 6B(Homo sapiens (Human))TBA
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific demethylase 6B(Homo sapiens (Human))TBA
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))TBA
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  4.20E+4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))TBA
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  4.46E+4nMAssay Description:Inhibition of KDM6B (unknown origin) expressed in Escherichia coli using H3 (21 to 44 residues) K27Me3-GGK-Biotin JMJD3 Cognate Ligand/10 uM alpha-ke...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed