Found 5 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50151435' TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity to mGLUR2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 2.38nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]-MGS0008More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 2 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at mGLUR2 expressed in CHO cells assessed as inhibition of glutamate-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration for agonistic activity towards metabotropic glutamate receptor 2 of rat expressed in CHO cellsMore data for this Ligand-Target Pair
