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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM375244'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 5


(Homo sapiens (Human))
BDBM375244
PNG
(US10253018, Example 10)
Show SMILES CC(C)Oc1nc2cc(F)c(cc2nc1OC(C)C)C(=O)Nc1cccc(n1)-c1nnnn1C(C)C
Show InChI InChI=1S/C24H27FN8O3/c1-12(2)33-21(30-31-32-33)17-8-7-9-20(26-17)29-22(34)15-10-18-19(11-16(15)25)28-24(36-14(5)6)23(27-18)35-13(3)4/h7-14H,1-6H3,(H,26,29,34)
PDB

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UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



Enanta Pharmaceuticals Inc

US Patent


Assay Description
ASK1 was purchased from Thermofisher (Catalogue # PV4011), ATP was purchased from Sigma (Catalogue # A7699), HTRF® KinEASE™ Assay System was obtained...


US Patent US10253018 (2019)


BindingDB Entry DOI: 10.7270/Q2TX3HPP
More data for this
Ligand-Target Pair