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Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 4' and Ligand = 'BDBM225898'
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225898(MAP16 | US9592235, Example 248 | US9855269, Compou...)
Affinity DataKi:  78.3nM IC50:  65.7nMAssay Description:Z'Lyte AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225898(MAP16 | US9592235, Example 248 | US9855269, Compou...)
Affinity DataIC50:  65.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225898(MAP16 | US9592235, Example 248 | US9855269, Compou...)
Affinity DataIC50:  65.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent