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Found 8 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50170678'
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50170678((3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3...)
Affinity DataKi:  12nMAssay Description:Inhibition of [125I]- IOXY binding to human Opioid receptor mu1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50170678((3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]IOXY from human recombinant mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50170678((3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3...)
Affinity DataKi:  12nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50170678((3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3...)
Affinity DataEC50:  3.40E+3nMAssay Description:Agonist activity at human mu opiod receptor expressed in CHO-K1 cells assessed as stimulation of beta-arrestin recruitment measured after 90 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50170678((3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human mu opiod receptor expressed in CHO-K1 cells assessed as increase in forskolin induced cAMP production measured after 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50170678((3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at MOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50170678((3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human recombinant mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50170678((3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3...)
Affinity DataEC50:  500nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding to Opioid receptor mu1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed