Found 33 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50003359' 
Affinity DataKi: 7.90nMAssay Description:Binding affinity to human cloned muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Affinity towards human M1 receptor expressed in CHO cells using [3H]QNB as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Binding affinity towards M1 muscarinic receptor expressed in A9 L cells by diaplacing [3H]-(R)-QNB radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 0.00800nMAssay Description:Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]-Pz as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-pirenzepine (Pz) from rat hippocampus muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]-pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Displacement of [3H]-oxotremorine-M (Oxo-M) from rat hippocampus muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]-oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 6.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 6 in continuous presence of radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 in continuous presence of radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 955nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 by wash-resistant binding methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMpH: 6.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 6 by wash-resistant binding methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+3nMAssay Description:Agonistic activity against M1 muscarinic receptor expressed in NIH 3T3 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Effective concentration required for stimulation of phosphoinositol (PI) hydrolysis in the A9 L cell line transfected with the Muscarinic acetylcholi...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 135nMAssay Description:Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.More data for this Ligand-Target Pair
Affinity DataEC50: 5.70E+3nMAssay Description:Tested against Muscarinic acetylcholine receptor M1 expressed in A9 L cell lineMore data for this Ligand-Target Pair
Affinity DataEC50: 67nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 57nMAssay Description:Agonistic activity against M1 muscarinic receptor expressed in A9 L cells.More data for this Ligand-Target Pair
Affinity DataEC50: 1.62E+4nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based beta-arrestin engagement assayMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein engagement assayMore data for this Ligand-Target Pair
