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Found 3 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM772'
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM772(Benzamidine | CHEMBL79897 | [amino(phenyl)methylid...)
Affinity DataKi:  2.90E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM772(Benzamidine | CHEMBL79897 | [amino(phenyl)methylid...)
Affinity DataKi:  3.20E+5nM ΔG°:  -19.7kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM772(Benzamidine | CHEMBL79897 | [amino(phenyl)methylid...)
Affinity DataIC50:  4.40E+5nMpH: 8.0 T: 2°CAssay Description:The cleavage of the substrate was followed by monitoring the change in fluorescence at 460 nm (excitation at 365 nm) for 25 min at room temperature o...More data for this Ligand-Target Pair