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Found 6 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM11243'
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataKi: >1.00E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of SARS-CoV-2 MProMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
University Of Bonn

LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataIC50: >2.00E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataIC50: >2.00E+4nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataIC50:  8.00E+5nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed