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Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM496877'
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496877(indole chloropyridinyl-ester derived, 7f)
Affinity DataIC50:  470nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496877(indole chloropyridinyl-ester derived, 7f)
Affinity DataEC50:  5.67E+4nMAssay Description:VeroE6 cells and TMPRSS2-overexpressing VeroE6 (VeroE6TMPRSS2) cells were obtained from the Japanese Collection of Research Bioresource...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed